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Preliminary evaluation of a three-dimensional, customized, and preformed titanium mesh in peri-implant alveolar bone regeneration

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Á¤°Ü¿î, ÀüÀçÀ±, Ȳ°æ±Õ, ¹ÚâÁÖ,
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Á¤°Ü¿î ( Jung Gyu-Un ) - Ewha Womans University Mokdong Hospital Department of Periodontology
ÀüÀçÀ± ( Jeon Jae-Yun ) - Hanyang University College of Medicine Department of Dentistry Division of Oral and Maxillofacial Surgery
Ȳ°æ±Õ ( Hwang Kyung-Gyun ) - Hanyang University College of Medicine Department of Dentistry Division of Oral and Maxillofacial Surgery
¹ÚâÁÖ ( Park Chang-Joo ) - Hanyang University College of Medicine Department of Dentistry Division of Oral and Maxillofacial Surgery

Abstract


Objectives: The purpose of this preliminary study is to evaluate the effectiveness of a customized, three-dimensional, preformed titanium mesh as a barrier membrane for peri-implant alveolar bone regeneration.

Materials and Methods: Ten patients were recruited for this study. At the time of implant placement, all patients had fenestration or a dehiscence defect around the implant fixture. A mixture of particulate intraoral autologous bone and freeze-dried bone allograft was applied to the defect in a 1 : 1 volume ratio and covered by the preformed titanium mesh. A core biopsy specimen was taken from the regenerated bone four months postoperatively. Patients were followed for 12 months after the definitive prosthesis was placed.

Results: Satisfactory bone regeneration with limited fibrous tissue was detected beneath the preformed titanium mesh. Histologic findings revealed that newly formed bones were well-incorporated into the allografts and connective tissue. New growth was composed of approximately 80% vital bone, 5% fibrous marrow tissue, and 15% remaining allograft. All implants were functional without any significant complications.

Conclusion: The use of preformed titanium mesh may support bone regeneration by maintaining space for new bone growth through its macro-pores. This preliminary study presents the efficacy of a preformed titanium mesh as a ready-to-use barrier membrane around peri-implant alveolar bone defect. This preformed mesh is also convenient to apply and to remove.

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Alveolar bone loss; Histology; Surgical mesh

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